https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24700 Wed 17 Nov 2021 16:31:18 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:55013 Wed 03 Apr 2024 11:01:53 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50196 Thu 06 Jul 2023 16:05:20 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25375 Sat 24 Mar 2018 07:39:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50096 1c 8.4 ± 1.6%) were included in this cross-sectional analysis. Carotid-femoral pulse wave velocity (cfPWV) was used to quantify arterial stiffness. Aerobic fitness (relative V̇O_2peak ) was determined via indirect calorimetry during maximal exercise testing. Central body fatness was determined using waist circumference. Data were analysed using hierarchical multiple regressions. After adjustment for sex and duration of T2D, each one standard deviation (SD) increase in age (8.68 years) was associated with a 0.63 m·s^-1 increase in cfPWV (β = 0.416, p = 0.001). Following adjustment for aerobic fitness and body fatness, the standardized β was unchanged (0.417). A one SD increase in waist circumference (13.9 cm) and relative V̇O_2peak (5.3 ml·kg^-1 ·min^-1 ) were associated with a similar magnitude of difference in cfPWV (0.47 m·s^-1 and -0.44 m·s^-1 , respectively). Therefore, age is a significant correlate of increased arterial stiffness in T2D, with higher aerobic fitness attenuating, and higher body fatness exacerbating, this increase. Interventions aimed at improving cardiovascular outcomes in people with T2D should target both increased aerobic fitness and reduced body fatness.]]> Mon 17 Jul 2023 11:57:25 AEST ]]>